Monday, September 30, 2019

Educatinal Technology

1- ) Examine three (3) of the issues you feel are most important in shaping the role of technology in education. Analyze why they are most important ones The role of the education in this global world is increasing each day. There are a lot of ways, strategies and approaches to increase quality of education. One of most effective way is integrating technology in to the education. That is called educational technology.There are a lot of advantages of technology in the class but I will give information about three advantages of technology in the classes which are freedom, equality of the education and creativity. Technology in the education is giving more freedom to teachers and students. How? As a mathematics teacher in a public school I can give examples from my own experiences. I use smart board and smart pad in my classes. I prepare my lesson plan as software and I reflect on the board or on the screen. While I am walking around the class I can teach.I don’t have spent my ti me for writing the definitions or questions and cleaning the board. I don’t have turn my back to the students which is helping me for classroom management. As another example when I am teaching geometric figures even three dimensional figures now my drawing is not a problem anymore. With Mimio smart board I can visualize better. My students have more time to learn. And I put my class notes to website for students who missed the day or who couldn’t understand well. They still have chance review everything that they missed.I think this is the most important issue for role of the technology in the education. It is giving more time for teaching. It is another sole role of the technology in teaching, giving equal opportunity to all students. There are a lot of people who are seeking for education but they cannot reach it because of lack school or teacher . Maybe it is not common in U. S. A but around the world it is common. For these people technology is only hope. Or some people like me who have to support a family and want to get a degree; online education is the only way.With technology everybody has an opportunity to learn. For some special and minor issues technology is helping us so much too, for instance I have a student who is dyslexic. To make him focus to class and understand better tablet computers are very helpful. In my country Turkish Government is giving free tablets to all students. The last and I think most important benefit of the educational technology is increasing creativity. With standing front of the board and giving lecture we cannot individualize the education.It is a known fact every bodies learning way and level is different, from this perspective each person is unique. Especially if there is a big diversity in the class lecturing will not help. And if all students learn the same thing with same way it will not develop their creativity conversely it will decrease the creativity. To enhance students’ creativity we have to integrate technology in the education. With this way the students can learn with their own way and level. There is a web site that I use in my math applying classes (www. studyisland. om) , at the beginning of the year students are taking a diagnostic test and depends their results system is giving a unique way to each student, may be the system is not perfect but the idea is so beautiful. In twenty first century we are aware of that education is more complicated than we taught. Teachers are facing with different problems such as dyslexia, ADHD/ADD, asperger syndrome. To individualize education technology is very helpful. Increasing technology using will develop creativity ,freedom and opportunity in the education. ———————– Page | 1 Page | 1

Sunday, September 29, 2019

Apply Ethics in Practice Essay

This brief synopsis as a human service worker in which I make every effort to help people, groups, and communities to triumph over their issues and struggles. As a human service worker I almost certainly would come across many ethical predicaments that involve susceptible issues such as discrimination, social unfairness, and oppression, poverty, substance abuse and mental health issues. As a human service worker or provider my personal principles may become an ethical difficulty with reference to discrimination of any sort because of my private belief but of course I am conscious of how many ethical standards that can be challenged if I allow my individual view to develop into concern. Nevertheless of course I identify with knowing and should no bet use as an unbiased conclusion unless the circumstances turn out to be dangerous to myself or the client involved. Next, if this circumstance come to pass then I would use the code of moral principles produced by the national association o f human service workers as a most important point addressing ethical predicament which it may cause. On the other hand, I was in a circumstance where a person that I was helping he was very serious and clear in his mind and full detail about who he wanted to work with and talk too. He was discriminating against a co worker because of skin color and race although we were on the job and others was watching him he decided to be rude and very sarcastic for no apparent reason. I wanted to voice my opinion but I didn’t but finally one day I decided to read the code of ethics at work and fill out a report on him with other co workers so that the discrimination could stop. It ended up being better than before the man was disciplined but functioning in the human service department there will be times when you do not agree with your client and your own principles could turn out to be an fair matter. My individual principles possibly will develop into an ethical concern if I meet a family unit where a close  relative is a drug user or a pregnant mother is a smoker. I am a well-built advocate in captivating concern of the happiness of offspring and unborn children in a drug badly treated atmosphere. I do not believe any close relatives ought to abuse drugs more than ever with child, it is not in favor of my ethical importance. I also be inclined to be very guarded when it comes to serving a family where whichever together parents or just one parent is a drug user. I want to make sure that the family be taken care of and will most importantly loving towards the children. Finally in conclusion I consider a situation to may have found myself, as a human service expert or professional, wherever I used private ideas may perhaps develop into an ethical matter and in closing apply ethics in all situations. Reference Dittmer, J. (2013). Ethics Applied. Retrieved from http://www.iep.utm.edu/ap.ethic

Saturday, September 28, 2019

Difference of Othello’s Behaviour in Act One and Act Two

English Literature – Othello How is Othello’s behaviour in Act Two different from his behaviour in Act One? How do you account for this change? What consequences do you think it will have? In Act One, Othello appeared to be in control of his emotions. When Brabantio confronts Othello, accusing him of stealing and raping his daughter Desdemona by means of witchcraft, Othello is calm and tells his men to stop the fighting.Although he is being accused of kidnapping and raping Desdemona, in which the person who commits the crime would be burnt to death, Othello shows that he is unafraid of danger, ready to risk everything for the woman he loves, and is able to command others despite facing the serious accusation. He is ready to face justice, and convince the Duke of Venice that he has done nothing wrong. This shows that he is brave and confident. When he speaks to the Duke, he speaks in a respectful manner.He also promises not to be distracted by Desdemona if he is allowed to bring her together to Cyprus. His manner and promise appears to us that he is a serious, sensible and rational person. However, he behaved differently in Act Two, when he arrives in Cyprus. His behaviour is sloppy. For example, he tells the people in Cyprus that, to celebrate the defeat of the Turkish fleet, they can ‘dance’, ‘make bonfires’, and ‘sport’, i. e. to have sex. He tells the people to have party time, giving license for people to behave as they like to.Unlike the serious person he appears to be in Act One, Othello seems to be overjoyed to meet his wife Desdemona in Cyprus safely and the defeat of the Turkish fleet, becoming irrational and insensitive to the people’s fear of another attack. When he comes ashore, meeting his wife, he is overjoyed, forgetting to announce the defeat of the Turkish fleet. He greets his wife, saying ‘O my fair warrior’, and kisses her several times. It appears that he has completely forgotten his promise, not to be distracted by Desdemona, to the Duke.Cassio and Iago, on another hand, have repeatedly refers to Desdemona as ‘general’s general’, and that she is ‘in charge’. This tells us that Othello is clearly distracted by his wife, preventing him from performing his duties, as observed by his lieutenant and ancient. In Act Two Scene Three, Othello admits he is not acting rationally and not performing his best. He says, â€Å"Now by heaven, my blood begins my safer guides to rule, and passion, having my best judgment collied, assays to lead the way. This tells us that Othello himself is conscious of what he is doing. He admits to acting irrationally, following his passion to rule. This shows that he is distracted by Desdemona, because only their love and marriage would lead to Othello’s overflow of passion. This may also show that Othello follows his heart, will and passion to act and rule. When Othello finds Cassio and Montano fighting, he asks Iago what has happened without confirming with others. He does not investigate thoroughly, as Iago has hidden some of the truth.He immediately takes Cassio off his office. This can be considered as an impulsive judgment. His change of behaviour in Act Two is due to the distraction from his wife Desdemona. Because of his newly-wedded wife presence, Othello is distracted and unable to perform his duties. He is led by his passion, which is affecting him because of his sexual interest in Desdemona and his joy to be reunited with her after the rough journey on the sea. Being away from Venice may also account for his change of behaviour.Since Othello remains below the Duke and Senators in Venice, he demonstrates respectful and brave manner, so that even the Duke calls him ‘valiant Othello’. However, in Cyprus, Othello becomes the person-in-command in the whole of Cyprus. The sudden swell in his authority and power may have contributed to his irratio nal judgments and actions. In Cyprus, Othello no longer has to act in the way he has promised the Duke. He can betray the Duke’s trust, because no one in Cyprus has the power or authority to stop him, or report him to the Duke back in Venice.He reveals his sloppy behaviour, and is clearly distracted by Desdemona’s presence, preventing him from acting rationally. With Othello’s change in behaviour, it may be easier for Iago to manipulate Othello and to carry out his plan to destroy Othello’s reputation. In Act Two, Othello reveals that he follows his passion to rule, and makes impulsive judgments without investigating thoroughly. Iago observes this, and therefore use Othello’s weakness to carry out his plan by telling Othello that Desdemona has been unfaithful.Since Iago knows that Othello will not investigate thoroughly if he tells him that Desdemona has been sleeping with Cassio, it will increase Iago’s success in destroying Othello’ s reputation. Other people can use Desdemona as a means to get what they want from Othello, as she has a great influence on her husband. For example, Cassio, after losing his job, hires a band to serenade Desdemona. Cassio tries to appeal to Desdemona, so that she may help him persuade Othello to give Cassio back his job.This may result in a corrupted government, with people using tactics to win Desdemona’s favour, instead of getting the job using their own talents or strength. Lastly, since Othello acts according to his passion, Iago can, by manipulating Othello, remove those who are against him, or whose who disrespects and insults him, like Cassio who calls him ‘Honest Iago’. This will result in lack of talents and observant people in Othello’s government, because all those who are against or disrespectful to Iago can be easily removed by Iago. Therefore, Othello’s government will become corrupted.

Friday, September 27, 2019

Introduction Essay Example | Topics and Well Written Essays - 250 words - 5

Introduction - Essay Example Because of these above features, the two plant species remain to be most ideal for population growth experiments (Clatworthy and Harper, pg 308). According to Harper et al (221), the main aim of this experiment will be concerned with competition for resources between L.minor and S.rotundifolia in a laboratory setting. There is a suggestion that interspecific competition will result into a dip in the growth rate of either species. This is brought about by factors such as leaf size which mean creation of plenty of own food and other nutrients thereby growing at an increased rate and healthier thus out competing the other. The same experiment will be focused at regulating environmental thereby observing the interspecific interactions between the two plant species by measuring growth rate and competitive effect. It is possible to make a simple model of floating aquatic plant population. This is attributed to the fact that it is possible to provide them with regulated environment in glass beakers with cultures. The parameters controlled are temperature and light intensity. In order to investigate interspecific competition, the two are to be grown in same culture. This will be followed by observation as the struggle for existence commences (Harper and Chancellor, pg 682). As for intraspecific competition, the culture will be of a single species of Lemna. For that experiment which is aimed at investigating increase in light supply or duration, L.minor is grown in cultures exposed to varying light intensities and duration. Clatworthy, J.N., Harper, J.L., Comparative biology of closely related species living in same area. Inter and intraspecific interference within cultures of Lemna spp. and Salvinia natans. J. Exp. Bot. 13, 307–324, 1962. Print. Harper,J . L. & Chancellor, A. P., The comparative biology of closely

Thursday, September 26, 2019

Demand, Supply and Market Equilibrium Research Paper

Demand, Supply and Market Equilibrium - Research Paper Example The next thing is the connection between the law of diminishing marginal utility and the law of demand. The article describes the law of diminishing marginal utility that every additional unit brings lower satisfaction than the previous one. Therefore, every additional unit is given a lower price. Thus it is connected with the law of demand that the lower the price the higher the quantity demanded. Demand is defined as the willingness and ability of a consumer to buy a product. It is inversely related to price. When the price of good increases, its demand decreases and vice versa. The quantity of a good the consumer is willing to buy at specific prices is called a demand schedule. It shows how demand changes with the price. The graphical presentation of a demand schedule is called a demand curve. Utility is relevant to our course as we need to know about utility of a product to clear our views about what people pursue and pay for. Demand and its connection with the law of diminishing utility is also significant as we need to know about demand to see what people want and how much they want of a specific commodity and thus decide how it can be supplied. (Schafermeyer, 2000) Now the price change only changes the quantity demanded of a product but there are certain factors that change the entire demand of a product. ... In addition to that, the number of consumers is also directly proportional to demand. Consumer tastes and preferences have a strong impact on the demand as well. A good might be cheaper but the consumer may reject it if it doesn’t suit him. Moreover, if consumers expect the price to rise, they buy more of the existing stock and thus the demand increases. When the demand increases, the curve shifts towards the right and when it falls it shifts towards the left. The factors affecting the demand are a part of the learning requirement of our course as they change a force that controls the market. (Schafermeyer, 2000) The article defines Supply as the willingness and ability of a firm to produce a good at given price in a certain time period. Like demand, supply also has a relation with price but it is a direct one instead of an indirect one. When the price of a good rises, its supply rises. The quantity of a good supplied at a range of prices is called a supply schedule. The graph ical presentation of the supply schedule is called supply curve. The supply curve and its basics are also significant according to the syllabus as the second force controlling the market. (Schafermeyer, 2000) Apart from price, the cost of production also affects the supply. If the production costs are high then the producers will be reluctant to produce the good to avoid losses at lower prices. The number of sellers in a market also determines how much quantity will be supplied. Furthermore, the price of related goods also affects the supply of an object as the producers will shift to the good with a higher price. Lastly, if a seller expects the price to go up in some time then he will reduce the supply and wait for the right time to

The Act of Reading in America Culture Essay Example | Topics and Well Written Essays - 750 words

The Act of Reading in America Culture - Essay Example This essay targets the current inclination towards reading that is prevalent in the American society and tries to lookup the reasons behind it. It was not very long ago that the greatest asset of the current generation's grandparents used to be was their large collection of books. Their best pastime was to indulge in the reading of books for hours and hours. Each person of the household was instructed to take extreme care of the books and to keep them clean and put them bake at their original places right after reading. Discussion upon the theme of the latest book being read by the family used to be the main modes of dinner table conferencing. All this seems like just a dream nowadays. The fast paced lives of the present times have bought a distant gap between man and what used to be his most cherished hobby-the reading of books. It would not be incorrect to say that the infusion, rather explosion of technology changed the mode of the entire American society. It is quite natural to r ealize that youngsters were and are mesmerized with the advancements technology bought to them due the fast pace associated with digital gadgets and the immediate responses social media and chat forums gave to youngsters but for many the transition being experienced by elders specially the older generation was not too comprehensible. They probably were mesmerized to see the way technology was changing life. The changes life was gone through with the help of technology were probably taking them into a world of fantasy making them neglect their most cherished pastimes. Assessing the above mentioned change many authors have discussed this transition. Mitchell Stephens mentions this issue in one of his remarkable works titled "The death of Reading" (1991) in the following words: " Our homes barely make room for reading. Those old islands of quiet -- libraries, studies and dens -- long ago were invaded by flat screens and Nintendos. Now they are called "family rooms" or, more accurately, "television rooms." And our architects seem to have given up providing us with bookshelves; instead they busy themselves designing "entertainment centers." (Stephens, 1991) The author highlights a very major fact by emphasizing that this infusion of technology was being taken very well in the sense that even the living styles of men were being shaped according to it. The architects also began making room for the attention laden technology rich devices and in order to make room for them omitted the conventional and much cherished book shelves that used to house memories of hours of family time spent together and the treasure of priceless book collections. The authors mentions that his arguments may not seem real statistically because figures showed a percentage increase in sales among the number of printed books being sold Also, there was an amazing fact that after fast food outlets, print book outlets were the next largest number of growing retail outlets in the society. But there was less good reason behind these figures. Most of the retail outlets showed that they did not have an increase in number of sales during the holiday season signifying that books were being sold merely as objects of gifts. Books were being trended as favorite gifts mainly because everyone knew they needed to a lot sometime for reading but were unable to do so. So in order to satisfy their feeling of guilt they would buy books as gifts instead. Stephens(1991) mentioned some more figures that the number of people who had admitted to have not read a book in the past year had doubled from 8 eight percent to sixteen percent since the last year. It was also

Wednesday, September 25, 2019

Litercy Criticisms on How The People In A Street Car Named Desire Research Paper

Litercy Criticisms on How The People In A Street Car Named Desire represent those of tennessee williams life - Research Paper Example Meaning of Streetcar Named Desire The play â€Å"Streetcar Named Desire† was written after William’s first success of â€Å"The Glass Menagerie† and was known to develop with his own cliche statement which he called a ‘streetcar named success.’ This was based on his early achievements as a playwright and with the inability to move in the correct direction with his next plays. The confusion which came from this success was one which was based on the ability to indulge in life while not carrying a sense of direction about future prospects. The result was William’s moving into a controversial lifestyle where he was able to indulge in drinking, fine dining and gambling (Torres, 162). The conflicts which were faced then combined with the understanding that William’s had of himself which led from fame to a self – destructive attitude. The overall plot line and the different actions which take place, as well as the main theme of the pla y, all show this specific attitude and the way in which William’s is reflecting about his life at this particular time (Bloom, 11). The writing of this specific book was also based on the philosophies and interpretations which William’s had during this time. He created a looking glass of his own life and how he had struggled then instantly broken through into success. This left him with the need to re-examine relationships, morality and the conflicts which occurred either in his own life or in general. The idea which he began to move around was to find the ideal of what was good. â€Å"Then what is good? The obsessive interest in human affairs, plus a certain amount of compassion and moral conviction, that first made the experience of living something that must be translated into pigment or music or bodily movement† (Williams, 22). The philosophy which William’s fell back on at this time then led him to delve into his personal relationships, specifically with his sister, and to re-examine the interest of his personal affairs and the way in which he believed he had interacted with them. It was this specific component that led to the questioning of his character and the reflection of this in his next play (Thompson, 47). Direct Relationships to Characters The different characters used throughout â€Å"A Streetcar Named Desire† are recorded as having a direct association with William’s life. The characters in the play are known to be representative of the family that William’s had, specifically in reference to Blanche, who is found to go through several brutal relationships and end up in a mental hospital. Blanche is known to be directly linked to William’s sister, Rose, who struggled with mental health for several years and later became incapacitated after a lobotomy. The problem and crisis which William’s associates with is reflective of watching his sister go through the victimization and with the concept of explaining the complexities, emotional conflicts and the deeply rooted problems of the mental health which he sees through his sister. Each of these become associated with Blanche and the struggles noted throughout the play with her mental health and relationships with others (Vlasopolos, 322). The character of Blanche is the main focus which William’

Tuesday, September 24, 2019

Final Essay Example | Topics and Well Written Essays - 1000 words - 15

Final - Essay Example The word antique has been outlined by the poet to differentiate between those who don’t believe and those who believe (Dickson, 2591). The bible for example has been utilized to alienate the non believers and the believers. The deeply held conviction among the believers is seen not to have any bearings. The believers who are less in numbers are trying to find God by finding out that relationship that existed between him and the people who lived long time ago as presented by the bible. The poet acknowledges that those looking for God’s guidance through the bible posses a relationship that is second hand to the loving and deeply personal God. Many of the boys who don’t believe tend to reject God because they believe that he is impersonal and outdated. She claims that the problem lies with the type of presentation that exists. The use of the word warble is however interesting. Calling song bird images to mind is a subtle nod aimed at bringing out her confidence in connection to the almighty God. She asserts that the people should be used to condemn people but has to lead them toward improving their relationships with the almighty God. She utilizes the poem in educating the youths and young men to seek God through studying the bible. She also advices preachers to avoid condemning the young men through use the bible. She uses the word; it didn’t condemn referring to the bible as the word of God (Dickson, 2591). Emily Dickson is seen to support the pagan and to criticize and make a mockery of God in most of her poems. The antireligious tone in most of her poems has been avoided in literature studies to paint a better picture to the society. The poet has used the bible as a mean of ensuring her message is able to reach the people. The term boys are symbolic and have been used to refer the many the people in the world. Dickson is easily appreciated and

Monday, September 23, 2019

Economic science Essay Example | Topics and Well Written Essays - 1000 words

Economic science - Essay Example In order to fully comprehend the phenomena of transaction cost and/or evolutionary economics, it is imperative that the concept of management accounting be fully understood as well. Management accounting may be defined in various manners. It is basically related to the use of accounting information by managers of organizations. It helps them in making prudent and timely decisions to run their businesses in an efficient and effective manner. "Transaction Cost Economics concerns itself with markets and hierarchies as alternative governance mechanisms for completing a set of transactions. Market forms of governance tend to rely on prices, competition, and contracts to keep all parties to an exchange informed of their rights and responsibilities it is based on two assumptions about economic actorseconomic transactions are intendedly rational, but only limitedly so and economic actors seek self-interest with guile." (http://findarticles.com/p/articles/mi_qa3933/is_199811/ai_n8812605/print) According to Williamson (1996), this type of economics is basically related to the, "governance of contractual relations" and it consists of three levels which can be easily understood by means of the schematic diagram shown below: The institutional environment helps us to understand and define that "rules of the game". This includes all those factors that may influence or result in a change in the "comparative governance costs leading to a reconfiguration of economic organization". Williamson has basically defined governance to be of three types; market, hybrid and hierarchy. The individual basically is a, "result of the strict assumption of opportunism (i.e., self -interest seeking with guile) and human cognition is subject to bounded rationality (i.e., "intendedly rational, but only limitedly so"). In addition, TCE views governance as the means, "by which to infuse order, thereby to mitigate conflict and realize mutual gains the key purpose of organization on which transaction cost economics focuses is that of adaptation, of which two kinds were distinguished: autonomous adaptation in response to changes in relative prices, and cooperative adaptation accomplished through administration. Not only do transactions have differing "needs" for adaptations of these two kinds, but governance structures have differing capacities to supply autonomous and cooperative adaptation". (Williamson 2000, pp. 12, 19-20) New Institutional Theory Oliver Williamson is popularly known as the founder of the New Institutional Theory (also called the Evolutionary Theories of Economics) and he also coined the term "institutional economics" in 1975. However, its origins can be traced back to the works of Coase (1937), Hayek (1937, 1945), Chandler (1962), Simon (1947), Arrow (1963), Davis and North (1971), Alchian and Demsetz (1972), Macneil (1978), Holmstrm (1979) and others. Various definitions for the new institutional theory can be found in literature. Rosenberg (2000,p. 70) has defined it as, "a mechanism blind variation and natural selection that operates everywhere and always throughout the universe." "The new institution

Sunday, September 22, 2019

The Role of Literacy in Society Essay Example for Free

The Role of Literacy in Society Essay Adult literacy is essential to the economics of modern nations. It is crucial to individuals to have proficient literacy skills to make a difference to their prosperity. In 2003 the National Assessment of Adult Literacy used the following as a definition of literacy: using printed and written information to function in society, to achieve ones goals, and to develop ones knowledge and potential. This definition does not simply mean comprehending text it includes the range of information-processing skills that adults use in home, work and community. Literacy can be subdivided into three different categories: prose literacy, document literacy, and quantitative literacy. Prose literacy is defined as editorials, news stories, poems and fiction; these can be broken down into two categories expository prose and narrative prose. Expository prose is printed information that defines, describes, or informs. Narrative prose tells a story. Prose literacy is divided into 5 different level of learning. The first level of prose requires a person to read a short passage of text and locate a single piece of information that is identical with the information given. The second level of prose literacy requires a person to locate a single piece of information in the text, compare and contrast easily identifiable information based on criteria provided in the question, or integrate a few pieces of information, when distracters were present or when low level inferences were required. Level 3 of the prose requires a person to match literal or synonymous information in the text with that requested in the question, to integrate many pieces of information from dense or lengthy text, or to generate a response based on information that could be easily identified in the text. The fourth level requires a person to search through text and match multiple features, and to integrate multiple pieces of information from complex passages. The last level requires a person to search through text and match several features contained in dense text with a number of plausible distracters, to compare and contrast complex information, or to generate new information making high-level inferences. Document literacy is defined documents that are short forms or graphically displayed information found in everyday life. Some examples of document literacy are job applications, payroll forms, transportation schedule, etc. Document literacy is also divided up into five levels of document literacy. The first level is requires a person to locate information based on a literal match to the question or to enter information from personal knowledge into a document. The next level requires the reader to match a piece of information either when several distracters were present or when low-level inferences were required. Level 3 requires a person to integrate multiple pieces of information from one or more documents. The fourth level requires a person to perform multiple-feature matches, cycle through documents, and integrate information, all of which required high-level inferences. The fifth level requires a person to search through a complex displays that contained multiple distracters, to make high-level text-based inferences, and to use their specialized knowledge. Quantitative literacy is information that is displayed visually through graphs, charts, etc. Quantitative literacy like the other types of literacy is divided into five different levels. The first level requires a person to perform single, relatively simple arithmetic operations, such as addition, when the question included the numbers to be used and the arithmetic operation to be performed. The second level requires a person to locate numbers by matching the required information with that given, infer the necessary arithmetic operation, or perform an arithmetic operation when the tasks specified the numbers and the operation to be performed. The third level requires a person to locate numbers by matching the required information with that given, infer the necessary arithmetic operation and perform arithmetic operations on two or more numbers, or to solve a problem, when the numbers must be located in the text or document. The fourth level requires a person to perform two or more sequential arithmetic operations or a single arithmetic operation, when the quantities could be found in different displays, or when the operations had to be inferred from semantic information given or drawn from prior knowledge. The last level requires a person to perform multiple arithmetic operations sequentially, when the features of the problem had to be extracted from text; or when background knowledge was required to determine the quantities or operations needed. The relationship between economy and literacy is a crucial and well documented relationship. In a Canada study close to 50% of adults with a low literacy lived in low-income households, compared with only 8% of adults with high literacy lived in high-level incomes. This clearly shows what low literacy is capable of doing to the economy of the country. Also during that study it found that the risk of living in a household below the poverty lines is six times greater for a person that is at level one than someone that is at level four or five. It did say however the risk is significantly decreased from 50 percent to 22% if the level of literacy is increased from the first level to the second level. The other interesting fact is that women make about half of what men. This translates to all levels of literacy no matter what level of literacy it seems that women make about half of what the men make in that literacy level. If more of the population were literate it would increase the wealth of the entire nation. In conclusion it is clear that adult literacy is essential to the economics of modern nations. Many are below literacy level and these effects the economics of a country because the low literacy directly affects the wealth of an individual thus effecting countries wealth. Bibliography 1. The Value of Words: Literacy and Economic Security in Canada, Vivian Shalla and Grant Schellenberg The Centre for International Statistics Canadian Council on Social Development 2. Literacy in a thousand words. Beatriz Pont and Patrick Werquin, Education and Training Division, Directorate for Employment, Labour and Social Affairs Published: November 2000 3. Hughes, Languages and writing from class.

Saturday, September 21, 2019

Synthesis and Growth of HAp Crystals

Synthesis and Growth of HAp Crystals Results and discussions Synthesis of HAp/Chitosan/Dopamine films Two types of HAp-chitosan composite films were prepared: HAp-chitosan films with and without dopamine (Figure 1). The weight ratio between HAp and chitosan in the films was fixed to 50 wt% since the HAp content in human bones is about 50-70wt% in dry weight28-30. In comparison with the 50 wt% HAp-chitosan, 70 wt% HAp-chitosan films containing dopamine were also generated, but this composite was too brittle to be used as hard tissue substitute. HAp-chitosan films were successfully casted and the films were slightly yellow in color. Dopamine containing HAp-chitosan films were also casted and the color was changed to dark brown. The color alteration of the films was due to the oxidation of dopamine that formed phenolic tanning compounds19,31. Based on the previous studies, wet precipitation methods were carried out to synthesize a nano-HAp in the presence of chitosan and its derivatives13,16. Chitosan strongly interacted with HAp and regulated the anisotropic growth of crystalline HA. I n addition, it was revealed that dopamine can also facilitate the growth of the HAp crystals along the c-axis21. Therefore, the synthesis and growth of HAp crystals in the presence of both chitosan and dopamine were examined by FTIR, XRD and SEM before conducting the mechanical analysis and water uptake analysis. FTIR analysis and Wide-angle X-Ray Diffraction FTIR spectra of the composite films are shown in Figure 1. Generally, hydroxyl and phosphate bands of HAp and characteristic peaks of chitosan are present in all of the composites FTIR spectra regardless of dopamine addition. More specifically, FTIR spectra of the composites showed the identity bands of HAp; stretching and bending vibration modes from the phosphate groups () were identified at absorption bands of 898 1095 cm-1 and 477 660 cm-1 respectively. The combination band of hydroxyl (O-H) bending and libration modes was observed at 630 cm-1. Furthermore, observed band at about 3600 cm-1 indicated the O-H stretching. On the other hand, several typical chitosan absorption peaks of 1150, 1375, 1640 cm-1and 2900 cm-1were observed in the chitosan containing composites. Peak at 1150 cm-1 was indicating glucosamine unit. The peak observed at 1640 cm-1 represents amide I (C=O) and anti-symmetric NH3 deformation. The band appearing at 1599 cm-1is attributed to amide II bands. Both am ide I and amide II show a hydrogen bond between –NH2 and –OH of HAp. Peak at 2900 cm-1 represent the –CH2 backbone. In the dopamine containing composite, the polyphenolic content resembled by phenolic COH peak that was discerned at 1260 cm-1. Moreover, both of aromatic C=C and COO bands were also observed at 1600-1650 cm-1 FTIR is an appropriate technique to observe the composite constituent interaction. It measures the frequencies at which chemical functional groups absorb as the result of the sample’s chemical interaction. In this regards, the appearance of glucosamine unit band at 1150 cm-1 that overlap with the stretching vibrations bands of HAp indicated that HAp crystals were formed on the chitosan molecules through certain interaction. In addition, chitosan interaction with ions by means of phosphorylation were also identified by the emergence shoulder at 1220 cm-1 and an increased at 1064 cm-1 absorption peaks of the chitosan containing composites spectra12. Chitosan has great affinity to react with ions without pH dependent13. This interaction makes chitosan tend to undergo phosphorylation in acid, basic and neutral solutions. In the presence of the phosphorilated groups, chitosan can strongly bind with intermediate form of HAp, amorphous calcium phosphate (ACP), and impose constrain ts of ACP subsequently lead to crystalline HAp formation13. Furthermore, chelation of calcium ions by phosphate functionalities may also induce the formation of crystalline HAp. The XRD spectra of the samples with or without dopamine also support the existence of HAp crystalline phase in the composite films. Most peaks in the XRD spectra of the samples could be indexed to the known HAp structure (Ca10(PO4)6) with characteristic peaks at 2ÃŽ ¸ regions of 26Â º, 29Â º, 32-34Â º, 40Â º, 46-54Â º, which are consistent with HAp phase (JCPDF #09-0432), confirming that the phase was formed in all samples13,32. However, the crystallinity of HAp in the chitosan-HAp composite films was lower than 100% HAp powder due to the presence of chitosan. The broad peak around 20Â º is an indicative peak for chitosan in the composite film regardless of dopamine addition13. Interestingly, some evidence which support anisotropic growth of Hap in the presence of dopamine were shown in the XRD spectra. The intensities of HAP diffractions relating to (002), (300) and (211) peaks (at 2ÃŽ ¸ of 26 Â º, 32 Â º, 33 Â º respectively) were measured. The ratio of the measured diffra ction intensity of c-axis (002) to another direction was used to determine the orientation degree. The XRD results after Gaussian Fit indicates that the (002) to (300) intensity ratio of 50% HAp samples with and without dopamine was 0.17 and 0.45 respectively. This indicated the preferential orientation of the HAp growth in the c-axis was significantly increased with the presence of dopamine. Additional broad peaks (~10Â º ~15Â º) were observed in the dopamine containing film. It indicates that the addition of dopamine induced structural changes in d-spacing over 0.6-0.9 nm in the film due to dopamine-mediated crosslinking, or dopamine-mediated HAp growth. Overall, XRD spectra suggest that the aspect ratio and anisotropy increased in the dopamine containing HAp/chitosan composite. SEM, TEM analysis and Cell Test Result To examine the effect of dopamine addition on the surface morphology, the dopamine-containing films were observed under SEM and TEM (Figure 3 and 4). The figures show a presence of nanorod particles in the composites with narrow and uniform particle size distribution in all samples. In the absence of dopamine, this structure is likely formed due to phosphorylation of chitosan which bind with phosphate precursor compounds and modulate the crystallization of HAp13,16. In the presence of dopamine, the aspect ratio of HAp was increased up to ~4.7 fold compared with control HAp in the absence of chitosan nor dopamine (figure x). For a comparison, in the 50 wt% composite, the aspect ratios are 2.4 and 4.5, without and with dopamine crosslink respectively. The dopamine effect is probably because of catecholic group from the dopamine bind with Ca2+ in HAp crystals formation 21. The pKa dopamine is ~8.9, dopamine was added while the pH decreased from ~8 to 4.2 The protonated cathecholic group of dopamine are possibly involved in HAp formation and regulate the one-dimensional growth of HAp crystals. This phenomenon is well agreed as the previous experiment result that polydopamine addition on HAp provides mechanism for surface-anchored catecholamine moieties to enrich the interface with calcium ions, facilitating the formation of hydroxyapatite crystals19.The addition of dopamine not only guides the anisotropic directional growth of hydroxyapatite crystals which increased its aspect ratio, but also changed the homogeneity of the grain distribution and shape of the nanostructure (Figure 5). To study the effect of HAp content on the aspect ratio of the nanostructure, the 25% and 70 wt% HAp-chitosan film with/without dopamine was synthesized. As the results, the aspect ratio is increases with increasing of HAp weight %. The 70 wt% with dopamine containing sample showed the highest aspect ratio. (Supporting figure X). The aspect ratio is a significant property of HAp related to the absorbability and fracture toughness of the samples. Higher aspect ratio known to have better adsorbability since it is proportional to the surface area of rods3, which are beneficial for cell attachment. However, aspect ratio alone is inadequate to identify the cellular affinity of sample, as a previous study suggested that surface roughness can also play an important role33. It was also found that aspect ratio and surface roughness of the composite film have a significant effect on the cell attachment and proliferation1. We tested MC-3T3 cells (mouse pre-osteoblast cell line) proliferation on the HAp-chitosan composite surfaces. To measure the dependence of MC-3T3 cell viability and proliferation on surface materials quantitatively, WST-8 [2-(2-methoxy-4-nitrophenyl)-3-(4-nitrophenyl)-5-(2,4-disulfophenyl)-2H-tetrazolium, monosodium salt] based cell counting assay was performed. WST-8 produced yellow-colored product (formazan) when it was reduced by dehydrogenases in living cells34,35. The levels of cell viability and proliferation on the sample that contains dopamine were slightly lower than others (Figure 6) suggesting that the increasing of HAps aspect ratio is not always beneficial because the cell viability was rather decreased. Nevertheless, the number of viable cells in the sample is still increased, yet at a slightly lower rate than the other sample. This is implying that this material would probably have no strong cytotoxicity. However, in vivo testing is remains to be proved the cytotoxicit y of the dopamine-containing composites.

Friday, September 20, 2019

Cancer and Reproducibility of Decisions

Cancer and Reproducibility of Decisions Urologic cancer: What about reproducibility of decision made at multidisciplinary team management? BAYOUD Y, LOOCK PY, MENARD J, MESSAOUDI R, RIPERT T, PIERREVELCIN J, KOZAL S, LEON P, KAMDOUM M, CHOLET I, LARRE S . Abstract: Introduction: The prostate cancer (PCa) treatment is multimodal. Thus multidisciplinary team management (MDTM) decision-making process appears as a tool to answer all aspects of PCa. To evaluate the reproducibility of therapeutic decisions made at MDTM. Materials and Methods: We compared therapeutic decisions of PCa by presenting the same file of patient under a fake identity after 6 to 12 months from the first presentation. Forty-nine files of radical prostatectomy (RP) (28 pT2, 21 pT3) performed for clinical localized PCa were represented at MDTM which included urologist, oncologist, pathologist and radiologist. Analysis of therapeutic decisions comprised criteria as: TNM stage, Gleason score, margin status and comorbidities. The reproducibility was assessed statistically by Kappa coefficient. Results: Forty-nine file of radical prostatectomy (RP). The mean age was similar in both groups. The mean PSA was 8,32 ng/ ml (3,56-19,5) in pT2 group and 9.4ng/ml (3,8-22) in pT3 group. The margin status was positive in 25% and 47,6% respectively in pT2 and pT3 group. Decision made for pT2 group were the same in 100% case (k=1). In the group of pT3 (n=21), 33% of decision were different at second MDTM, especially for pT3b with only 29% reproducible decision (k= 0,1). Concerning pT3a, 86% of decision were reproducible (k= 0,74). Conclusion: We showed a reliability and reproducibility of decision made at MDTM when guidelines are well defined. The therapeutic attitudes were less reproducible in locally advanced PCa but decision concerning those cases should be made in the setting of guidelines. Key words: Cancer, Kappa coefficient, Prostate, multidisciplinary, Reproducibility. INTRODUCTION: The prostate cancer (PCa) is the most frequent cancer in men as well in Europe and USA (1). The PCa counts for 11% of all men cancers and it’s responsible for 9% of the mortality by cancer in men in Europe. In France in 2010, the incidence of PCa was 71577 cases and the related mortality of PCa at the same year was 8791 deaths which represent a 2.5% less mortality per year during last years (2). The multidisciplinary team management becomes an obligation for all oncologic fields as mentioned by the French government law: cancer program 2003-2007, this program stipulate that each new patient should benefit from MDTM decision-making process, organize the setting of MDTM and also gives tools to develop trials of research for a new diagnosis and therapeutic arsenal (3). Some urologists express some doubt about the interest of MDTM because of it’s a new burden without assigned budget while others see in the MDTM an equality of chance of patients, and possibility to include patients in trials and protocols. Number of European study showed the interest of MDTM and its beneficial impact on survival (4, 5). The efficiency of decisions made at MDTM is obvious but the evidence about their reproducibility remains doubtful. Through patients underwent a radical prostatectomy (RP) for localized prostate cancer (PCa) and represented identically, we evaluated a reproducibility of decision made at MDTM. Materials and Methods: From January 2011 to March 2012, 183 patients underwent radical prostatectomy for localized PCa, all of them were presented at MDTM and decision of diagnosis and treatment validated. Within those patients some files were selected prospectively for a second presentation. All of patients were presented identically under a fake identity 6 to 12 months later. Each file contained a full filled form including all decision- making parameters concerning patient (appendix 1). Patients were selected after agreement of their urologist who didn’t participate at decision making process at a second presentation. We also presented a case of patient which can be susceptible for debate and distinguished two groups. First one with localized PCa with or without positive margins (pT2 R0 or R1) and second one with advanced PCa (pT3a or b, R0 or R1) regarding 2002 pTNM classification. Criteria of selection was to select patients with localized and advanced PCa, we also selected those at low and high risk of local and systemic relapse based on pTNM and gleason score, two only important parameters  «predicting local and systemic relapse after RP » we had at this moment of decision making process (1). Thus we tried to have each half of group with gleason score at low and high risk of relapse. The group of pT2 comprised approximately 50% of patient with gleason score > 6 and the group of pT3 comprised approximately 50% of patient with gleason score ≠¤ 3+4 (table 1). We compared a decision made for each patient in both MDTM. All decisions were made accordingly to usual criteria as pTNM stage, Gleason score, margin status, comorbidities and choice of patients. MDTM comprised 5 urologists’ seniors and 2 juniors, 1 pathologist, 1 medical oncologist, 1 radiotherapist and 1 radiologist and organized weekly. The statistical analysis chosen for comparison between first and second decision made at MDTM was Kappa coefficient which scale vary from non-agreement to perfect. The coefficient Kappa is a statistical tool to assess reproducibility. It also allows an estimate of concordance of qualitative judgments for the same situations by two different observers (6). We compared all criteria of study with t-test for independent samples using means ±SD. Results: From January 2011 to March 2012, 183 patients underwent RP for localized PCa. From this population forty nine patients were selected prospectively and distribution of patients was as follows: 28 pT2c, 21 pT3 (14 pT3a and 7 pT3b). Baseline criteria of patient group and t-test are resumed in table 1. We observed a reproducibility of 100 % of the group of pT2c independently of the margin status and Gleason score. Kappa coefficient was perfect (ÃŽ º=1). In the group of pT3a, decisions were reproducible in 86% cases, with therapeutic attitude putting in balance surveillance or extra beam radiation therapy (EBRT) (figure 1). The distribution of decisions was as follows: 28% for EBRT, 72% for surveillance at MDTM 1 and 14% for EBRT, 86% for surveillance. The coefficient Kappa was substantial with a value of 0,74. In the group of pT3b, decisions were reproducible in only 29% cases. Therapeutic decisions were EBRT plus androgen deprivation therapy (ADT) in 71% patients and surveillance in 29% patients at MDTM 1, while therapeutic decisions at MDTM 2 were 14,5% for EBRT, 14,5% for EBRT plus androgen deprivation therapy and 71% for surveillance (Figure 2). The Kappa coefficient was slight with a value of 0,1. Discussion: Our study showed the pertinence of MDTM recommended by Law of cancer program 2003-2007 (3). Many European studies showed the interest of MDTM (4, 5), but number of urologists expresses some doubts about benefits, exposing as argument a new burden without assigned budget. This position is partly supported by Asher PL et al, they reported in 124 cases of urological cancer, MDTM changed therapeutic attitude in only 2% cases, thus authors suggested that urologist could presented only few patients to MDTM which reduced significantly a working cost without compromising therapeutic patient’s chance (7). Van Belle S showed that MDTM established by the Belgian governmental program was a success thanks to specifically assigned budget. Authors reported also indirect evidence between MDTM and survival rate of cancer in Belgium because it’s within the five best European rates (2,3 and (8) This hypothesis was sustained by results of Sternberg CN et al study, they concluded of beneficial effect of MDTM on free recurrence survival of PCa in patients at high risk of recurrence, in particular phase III of TAX 3501 where was compared treatment with immediate or differed ADT with or without docetaxel after RP (9). Our study showed reliability and reproducibility of decisions made at MDTM. This is valid in pT2 patients group in whom 100% of reproducibility was observed, while pT3a patients group showed 86% reproducibility (ÃŽ º = 0.74). However pT3b patients group showed worse rate of reproducibility with 29% (ÃŽ º = 0.1), this result should be interpreted with caution considering the smallness of sample (n=7). Further studies with biggest sample are mandatory to make conclusion. Those cases are still complex situations demanding MDTM decision-making process. The lack of well-defined recommendations certainly contributes to the weak rate of reproducibility of decision made at MDTM for locally advanced PCa. GETUG 17 trial which compares immediate EBRT associated to ADT versus deferred EBRT at biochemical recurrence with ADT for patients underwent RP in whom definitive pathology result is pT3 R1( R1: positive surgical margins) will contribute to clarify recommendations. The interest of MDTM is to include patients in the same trial. To support this idea, Nguyen TD et al showed in their study for breast cancer which recommendations are well designed that 92% of MDTM decisions were in accordance to recommendations and 96% of these decisions were followed by patient’s responsible doctor. They conclude also of the interest of including patients in trial (10). The same conclusions were reported by Carducci MA et al, they surveyed prospectively 8 cancers in 6 hospitals, and they showed that 128 patients of 153 (84%) benefited from specific therapeutic decisions thanks to MDTM. Authors insisted on the interest of MDTM in advanced PCa and inclusion of patients in trial (11). Several studies seem to end on the interest of a tool to standardize and optimize the therapeutic decisions. Thus, Benjamin A et al reported significant differences in care of localized PCa in the United States of America. Between 2000 and 2001, 2775 cases of localized PCa were collected from 55160 patients. They considered many criteria as geographic location, type of institution (academic hospital or community hospital), pathology analysis and follow-up after treatment. Significant differences were observed regarding geographic origin and type of institution where treatment was provided. Besides criteria as tumor volume, extra capsular extension and pTNM stage were considered for making decision process respectively only in 37,1%, 68,6%, 48,2% (11). Hardly 55% of patients benefited from a follow-up (12). Clarke MG et al showed in cohort of 30 urologists for whom were subjected questionnaires representing patients’ scenarios with prostate cancer, a mean of 3 cues from 9 were used to make therapeutic decision. Criteria as life expectancy, digital rectal examination, age of patient and patient’s choice were rarely used. The authors also reported that urologists made a different therapeutic decision in 31,4% cases when they answered a same questionnaire at different time. They conclude that well defined recommendations and MDTM will standardize process of making decision and enhance reproducibility of decisions (13). These observations were also demonstrated by Wilson J et al in their study concerning 32 urologists from Great Britain, for whom 70 questionnaires representing medical history of prostate cancer were subjected. Thirteen questionnaires among 70 were repeated to evaluate intra- observer reproducibility. They reported that intra-observer reproducibility varied fro m 56% to 79%, while inter-observer reproducibility varied from 24% to 57%. Authors conclude on interest of standardizing therapeutic scheme and working in MDTM process for better decision reproducibility(14). The MDTM appears as an answer to this need of optimizing the care process. Conclusion: In our study we showed a reliability and reproducibility of decision made at MDTM. Reproducibility is acquired when recommendations are well defined. This is proved for localized prostate cancer. On the other hand decisions for advanced prostate cancer were less reproducible even if decisions were made in the setting of recommendations of French Urologist association. These last cases justify more submission in the MDTM in the purpose to standardize the care process, facilitate inclusion in trial. This will allow having well-defined recommendations for complex cases of prostate cancer, and leading to best reproducibility of decision made at MDTM. BIBLIOGRAPHY: Heidenreich A, Aus G, Bolla M, et al. EAU guidelines on prostate cancer. European urology. 2008;53(1):68-80. Epub 2007/10/09. Salomon L, Azria D, Bastide C, et al. [Recommendations Onco-Urology 2010: Prostate cancer]. Progres en urologie : journal de lAssociation francaise durologie et de la Societe francaise durologie. 2010;20 Suppl 4:S217-51. Epub 2010/12/07. Recommandations en Onco-Urologie 2010: Cancer de la prostate. Plan cancer 2003-2007 (French Government Law ): http://www.afssa.fr/ET/DocumentsET/plan cancer.pdf Verdecchia A, Francisci S, Brenner H, et al. Recent cancer survival in Europe: a 2000- 02 period analysis of EUROCARE-4 data. The lancet oncology. 2007;8(9):784-96. Epub 2007/08/24. Berrino F, De Angelis R, Sant M, et al. Survival for eight major cancers and all cancers combined for European adults diagnosed in 1995-99: results of the EUROCARE-4 study. The lancet oncology. 2007;8(9):773-83. Epub 2007/08/24. Bergeri I, Michel R, Boutin JP. [Everything (or almost everything) about the Kappa coefficient]. Medecine tropicale : revue du Corps de sante colonial. 2002;62(6):634-6. Epub 2003/05/07. Pour tout savoir ou presque sur le coefficient Kappa. Acher PL, Young AJ, Etherington-Foy R, McCahy PJ, Deane AM. Improving outcomes in urological cancers: the impact of multidisciplinary team meetings. Int J Surg. 2005;3(2):121-3. Epub 2007/04/28. Van Belle S. How to implement the multidisciplinary approach in prostate cancer management: the Belgian model. BJU international. 2008;101 Suppl 2:2-4. Epub 2008/03/01. Sternberg CN, Krainer M, Oh WK, et al. The medical management of prostate cancer: a multidisciplinary team approach. BJU international. 2007;99(1):22-7. Epub 2006/09/08. Nguyen TD, Legrand P, Devie I, Cauchois A, Eymard JC. [Qualitative assessment of the multidisciplinary tumor board in breast cancer]. Bulletin du cancer. 2008;95(2):247-51. Epub 2008/02/29. Evaluation qualitative de la reunion de concertation pluridisciplinaire de cancerologie mammaire. Carducci MA, Carroll PR. Multidisciplinary management of advanced prostate cancer: changing perspectives on referring patients and enhancing collaboration between oncologists and urologists in clinical trials. Urology. 2005;65(5 Suppl):18-22; discussion Epub 2005/05/12. Spencer BA, Miller DC, Litwin MS, et al. Variations in quality of care for men with early-stage prostate cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2008;26(22):3735-42. Epub 2008/08/02. Clarke MG, Wilson JR, Kennedy KP, MacDonagh RP. Clinical judgment analysis of the parameters used by consultant urologists in the management of prostate cancer. The Journal of urology. 2007;178(1):98-102. Epub 2007/05/15. Wilson J, Kennedy K, Ewings P, Macdonagh R. Analysis of consultant decision- making in the management of prostate cancer. Prostate cancer and prostatic diseases. 2008;11(3):288-93. Epub 2007/10/31. Table1:Baselinecharacteristicsofpatientsgroupandt-testof independent sample Figure 1: Therapeutic decisions made for pT3aN0M0 group at MDTM 1 and 2 Figure 2: Therapeutic decisions made for pT3bN0M0 group at MDTM 1 and 2 APPENDIX 1: Initial location :Date of diagnosis : DD/MM/YYYY Clinical TNM stage: Pathology result (specimen): pT: XX pN: XX M: XX Status margin (R): Rx Motive: Diagnosis à ¯Ã‚ Ã‚ ¯Therapeutic decision à ¯Ã‚ Ã‚ ¯ Therapeutic adjustment à ¯Ã‚ Ã‚ ¯Ãƒ ¯Ã¢â€š ¬Ã‚  Surveillance after treatment à ¯Ã‚ Ã‚ ¯Ãƒ ¯Ã¢â€š ¬Ã‚  Another motiveà ¯Ã‚ Ã‚ ¯ Medical history : Result of exams : (ex CT scan, MRI, Bone scan, medical notice of colleague †¦Ã¢â‚¬ ¦) Patient’s choice : WHO general health status :0 à ¯Ã‚ Ã‚ ¯Ãƒ ¯Ã¢â€š ¬Ã‚  1 à ¯Ã‚ Ã‚ ¯2 à ¯Ã‚ Ã‚ ¯3 à ¯Ã‚ Ã‚ ¯4 à ¯Ã‚ Ã‚ ¯ Comorbidities: Therapeutic suggestion : Final thà ©rapeutic decision :

Thursday, September 19, 2019

Its All Downhill :: Personal Narrative Essay Example

It's All Downhill From Here 8:02 a.m. Saturday. It's still dark, as usual, on these cold, winter days. Everybody else is still sleeping and enjoying the comfprting heat of their beds. I crack open the locked window by my bed, an act some deemed downright idiotic. I strip off my pj's, throw on my robe, and head for the shower. Drying off, I think about where I am abou to go. I dress piece by layered piece. I can't wait to hit the slopes! I round up my tools: body, boards, boots, bindings. Everything is in working order and ready for take-off. As I open the front door, I am shocked by the cold and fight my way through the wind to my car. I turn the key and put the heater on full blast. I am almost there. I step out of my car and survey the parking lot. Not too many cars. That's the way I like it. I take a deep breath and savor the frsh air. Already, I can feel the pressure of deadlines lifted off my chest. I strap my skis on, and prepare not just to tackle a run but other situations in my life as well. I skate over to the first pitch of the double diamond slope, and map out where I will take the first couple turns. It is almost like I am assessing my goals in life: getting accepted into Syracuse, owning a house in Colorado, raising a healthy family. I appreciate the sound of carving the first turn as if it was my very last. The crunching of the snow under my feet empowers me to crush the antagonists in my everyday life. The second and third turns secure my self-confidence. Only with the fourth turn do I start to realize that things are not always that easy. I heard it said often, "It's easier said than done." I never believed it until now. I only skid slightly over a patch of ice, but it is enough to start my heart thumping. I am suddenly aware that to finish this run or to reach my goals, I have to be ready for the tricky spots. I know that at any moment I could fall and be forced to start over. My lifetime goals can be affected by any number of things - grades slipping, drugs and alcohol - and I have to be ready to handle anything.

Wednesday, September 18, 2019

Essay on Gregor as Christ in Kafkas Metamorphosis -- Metamorphosis es

Gregor as Christ in Kafka's Metamorphosis In his "Metamorphosis", Kafka utilizes an allegorical technique to compare Gregor's sacrifices to those of Jesus in the Bible. Ultimately, both Gregor and Jesus sacrifice their lives so that they can help their loved ones, despite betrayal.   Kafka uses this biblical allegory to illustrate Gregor's Christ-like actions. In the Bible, God, sacrifices his only son, a respectable, revered "heavenly" figure, allowing Jesus to live amongst sinful people. In human form, Jesus treats the common people's illnesses and performs miracles to help them; above all, he cares for them and loves them.   Jesus is selfless, endlessly devoting himself to helping and serving others, and ensuring that they will have a better life by showing them "the way" to God.   Jesus sacrifices his life in heaven to come to Earth and help his people. Just as Jesus makes personal sacrifices to help his people, Gregor similarly sacrifices his dreams and happiness to provide a good life for his family.   Gregor's life revolves around his job as a travelling salesman.   He is committed to his work, although he dislikes his job, "what a gruelling job I've picked.   If I didn't hold back for my parents' sake, I would have quit long ago" (4).   Gregor's life lacks comfort and joy; he is constantly travelling, and is unable to form quality relationships.   However, he sacrifices his dreams for future happiness so that he can provide for his family.   As the sole 'breadwinner' of his family, Gregor keeps only a few dollars from his paycheque each month, using the rest to pay family debts and sending the money home to his parents.   His family is completely dependent on him for financial security, and Gregor's generosity preven... ...trayed by his family, he is imprisoned in his room; however, he "thought back on his family with deep emotion and love".   His affection for his family results in his conviction that he must disappear, so that he can bring them happiness and peace.   Gregor sacrifices his life and dies during the night to save his family from hardship.   He loves them unconditionally, like Jesus loves his people, and does not criticise them for betraying and mistreating him. Gregor's final sacrifice of his life is the strongest comparison of his Christ-like attributes. In Kafka's "The Metamorphosis" Gregor's sacrifices are shown to be Christ-like by the horrible treatment he receives from others, his betrayal by his family, and his selfless reactions and eventual death. Works Cited: Kafka, Franz. The Metamorphosis. Trans. and ed. Stanley Corngold. New York: Bantam, 1972.

Tuesday, September 17, 2019

Face and Social Media Essay

#1: Product – not just another knock-off Competing only on price was not what XiaoMi has chosen as their core strategy. Surely, their phones and tablets are cheaper than Apple’s and Samsung’s but, by far, not the cheapest ones in the market. There are cheaper smartphones that flood China, however all of them have a major flow – poor quality. Essentially, those devices are reverse-engineered versions of Samsung models built from cheaper materials. By coming up with a good quality phone at lower price range was the key strategic move that put XiaoMi firmly on the map. The phone has a robust case, high quality screen and a reasonable battery. It doesn’t break easily, unlike cheaper copycats that start having issues after just a few months of use. By building it’s own Android-based OS called MIUI, XiaoMi phones got new exciting features not found on standard Android devices as well as plenty of customization options. #2: Price – pay less now, pay more later XiaoMi has also realized that selling cheaper phones near their actual cost was not a sustainable long term strategy, so they decided to go with the Amazon’s model – just cover the cost of the devices and make money from selling content. Although, XiaoMi is often compared to Apple, especially considering the fact that their founder, Lei Jun, resembles Steve Jobs in his style and charisma, it is clear that XiaoMi’s true inspiration comes from Amazon. Also, XiaoMi mostly sells online which further reduces cost of sales and overheads related to brick and mortar stores or dealing with distributors and retailers. XiaoMi has also managed to harness the power of social media by not only broadcasting their messages and announcements but by actively engaging with their customers. Engineers are routinely encouraged to speak directly to consumers and use gathered feedback to refine software. #3: Place – gain strength at home first Although there are rumors of XiaoMi’s inevitable coming to North American and European markets, the company seems to stay focused on China with 97% of the shipments locally. It has been mentioned that their next target will be in South East Asia and, most likely, other BRIC countries. Recently, ex-Google executive, Hugo Barra, who himself hails from Brazil, has become new XiaoMi’s international face. It seems that the company is not in a rush to  go to more developed markets dominated by Apple and Samsung and prefers staying focused in its home base where the market is still booming. Perhaps, potential IP related troubles stemming from frequent accusations of possible infringements, also play role in choosing to stay away from US and EU for now. #4: Promotion – the power of word of mouth OK, this one got to be my favorite so I have to break it down. First of all, early on, they have pioneered flash style sales which were done with little or no advertising. Flash sales basically mean selling limited quantities during limited periods. They always create anticipation and urgency – great factors to win consumers’ minds and hearts. Needless to say, the units were sold quickly and talked over a lot all over China’s vibrant social media. Word of mouth marketing worked very well for XiaoMi and they continue to take full advantage of it. #5: Promotion – active use of social media XiaoMi has also managed to harness the power of social media by not only broadcasting their messages and announcements but by actively engaging with their customers. Engineers are routinely encouraged to speak directly to consumers and use gathered feedback to refine software. #6: Promotion – dedicated brand advocates Through its active role in social media, XiaoMi has also succeeded in building a dedicated fan base. Those Mi-fans are very active in social media and are, in some ways, similar to those hardcore Apple advocates that we are all familiar with. Mi-fans are always present at XiaoMi’s product launches where they are known for loud cheering and applauding. #7: Promotion – CEO as the face of the brand Last but not least, XiaoMi’s charismatic boss, Lei Jun, does a great job in making his brand look cool and current. He has put a face to a brand, something that traditional executives in China wouldn’t feel comfortable doing. Lei Jen’s similarity to Steve Jobs in the ways he talks about the brand is not a coincidence – the late Apple’s founder still holds an almost iconic image among Chinese.

Monday, September 16, 2019

Coasts Revision Notes – AQA Geography

1. Spring and Neap Tides Spring vs. Neap Tides Spring tides occur when the Earth, Sun and the Moon are all about in the same line. This causes the highest tidal range due to the strongest gravitational pulls with the high tides being the largest and the low tides being the smallest. Neap tides occur when the Earth, Sun and Moon are at 90 degrees which causes the gravitational pull to be less effective. This produces the lowest tidal range of tides. 1. Coastal Transport Long shore drift transports material along the coast. In the UK, the prevailing wind blows from the South West causing the waves to approach the southern coast at an angle of 45 degrees. Therefore material moves from the west to the east. The swash of the wave carries the material up to the beach at this angle. The bed load is moved along by rolling by traction however pebbles are lifted and bounced along the floor in a leap frog action – this is saltation. Lighter material is carried by suspension (such as grains of sand) and weak acids (e.g. carbonic acid from precipitation) may act on soluble rocks (carbonate rocks e.g. limestone) and move the material in solution. The backwash carries the material at 90 degrees- causing a zig-zag motion. Groynes may be in place to reduce this – however they can be expensive (around  £5,000 per groyne and are unasthecially pleasing) yet they do trap the sand. 1. Headland Formation Headland formation occurs when the bands rock type run perpendicular to the coast – this is known as a discordant coastline. The coast has alternating bands of resistant (hard) and less resistant (soft) rock – these types of rocks erode at different rates. The less resistant rock are eroded at a faster rate (through the processes of hydraulic action, abrasion and corrosion) and the more resistant rock erodes at a slower rate and protrudes out into the sea. Wave Refraction Now the headland is protruding out into the sea, this receives high energy waves. When the waves hit the coastline, they are refracted and they tend to ‘bend’ round the headland, into lower energy waves. These waves then deposit sediment and beaches eventually build up. Case Study: Purbeck coast, Dorset. The Eastern side is discordant. Headland – The foreland Purbeck Coast, Dorest. Geology – Chalk (made millions of years ago from Coccoliths). This headland is 1.3km wide. Bay – Swanage Bay made from Wealden & Purbeck bed clays. This bay is 2.5 km wide. 1. Causes of cliff collapse Coastal Reasons * When waves head towards the coastline and the sea gets shallower, friction in the bed slows the bottom of the waves and make them more elliptical. The crest of the wave rises and then it collapses. * Destructive waves are high frequency, and are high and deep. They are around 10-14 waves per minute and their strong backwash removes material. * The waves break at the base of the cliff where the wave energy is concentrated. * This part of the cliff experiences rapid erosion thorough – abrasion, where material carried by the waves (eg rocks) are hurled against it. Also, H.A where the pressure of the air in the cracks from the water compress and release which erodes it. * This forms a wave cut notch * Over time, under the force of gravity, the mass above the wave cut notch cannot hold and collapses. * This processes of collapsing continues and the cliff retreats back. * This then leaves behind a wave cut platform that is no more than 5 degrees at the Low Water Mark. * As the platform gets longer, the waves have to reach further and many dissipate reducing the rate of erosion. * Sub Arial processes erode the platform such as paddock and seaweed. * Case Study: Broad bench Dorset, cliff is mixture of clay and shale (headlands made of Portland stone). Extension is 200m of platform, height of cliff is 20 m. Part of Jurassic coast – world heritage site. Sub-Arial * Not directly linked to sea, but from land * Freeze Thaw – When the diurnal range is around 0 dregrees – Scottish Highlands – Water expands by around 9%. Fluccutations in pressure fragments of rock may break off. * Biological – Rabbits may burrow into the cliff and piddocks may also weaken the rock which may remove some of the rock. * Chemical weathering, CO2 found in rainwater may form carbonic acid when it rains – attacks the calcium carbonate such as in limestone. Mass Movement * Slumping – Rainfall infiltrates the soil, making it heaver. * The material moves downhill, leaving a exposed scarp face * Case Study – Holbeck Hall, Scarborough. * 1993 – dry weather cracked the clay. This made the rock impermeable due to hot dry conditions * Next two months 140mm of rain fell (prolonged rainfall) * This then therefore infiltrated the soft rock above, but lubricated the clay. * On 3rd of June – the land was slipping into sea at 3m per hour. Collapse of hotel. Rest of hotel had to be demolished and they owners sued the authority ‘breach of its duty and care’.

Sunday, September 15, 2019

Consumerism in America

Consumerism is assumed to be the basic pattern for the modern lifestyle in the USA. Some researchers even compare it with a kind of belief. It is essential to explore the nature of this phenomenon, including its development and the contemporary situation. In addition, it is useful to give a precise definition. Eventually, its consequences and effects are to be put under analysis.Consumerism is multifaceted, resulting in a significant influence on a variety of American life aspects. It is sure to have effects on a particular individual as well as on society as an entity. The â€Å"ideologists† of consumerism state that its principles are highly beneficial for consumers. However, nowadays, the majority of literature dedicated to disclosing the peculiarities of consumerism tends to incline to recognizing the preferably negative character of consumerism consequences for economy, social ethics and even environment etc.Though, the essence of the effects, especially, whether they are adverse or positive, needs a deep exploration. In America it seems that we are driven by the need to have more could this need to have more be fueled by something other than our inalienable rights to life, liberty, and the pursuit of happiness as mentioned in the constitution or, could this need be socially and, commercially driven.Consumerism developed within certain conditions, predetermining the inevitable appearing of such a phenomenon. The Industrial Revolution of the 1800s shifted the way of the economic history. For the very first time, it allowed products to be available in previously impossible huge quantities. Not to mention the fact that the increase in production in the late nineteenth and early twentieth century resulted in growing markets. This meant expanding the consuming class far beyond the middle and upper classes and to include the working classes (Beder, 2004). The population rates grow only three times between 1860 and 1920 while the production increased by 12   to 14 times (Beder, 2004).The major industrial facilities tried to go with the times. That was the reason that back in 1910, Henry Ford instituted the â€Å"line production system† in his Highland Park, Michigan plant (Chandler, 1976). In spite of the innovation being in particular ways relatively unsophisticated, that was the moment of transformation of the U.S. capacity to produce (Ewen, 1976). In addition, the high level of products availability can be easily explained by rapid cost rate decrease. Moreover, the unrestricted access naturally resulted in the flourishing of the Mass Consumption era (â€Å"History of American Consumerism†).The mechanisms of mass production determined the need for markets to become more dynamic. These dynamic changes had to include various aspects. Firstly, they needed to grow horizontally, meaning nationally, secondly, vertically (expanding into such social classes that were not previously among consumers), and, eventually, ideologi cally (Ewen, 1976). The population was forced to be habituated to give a response to the newly developed demands of productive machinery. The researchers emphasize that it was even a nationwide systematic plan aiming at providing the wide masses with more buying power (Ewen, 1976).As the result, the system of consumer production was freely growing. The mass manufacturer could not depend exclusively upon an elite market in order to respond to the productive capacity. Therefore, the products' mass producer was forced to take into consideration the whole United States, ensuring the competitiveness with the other manufacturers by producing enough goods quantity for reducing the cost to the sufficient rate (Ewen, 1976).Nevertheless, the philosophy of consumerism has undergone a number of changes. It was imposed that people are almost obliged to obtain not only necessary goods, but also pay special attention to the other factors. For instance, new model of a particular product has been co nsidered to be more efficient, meaning the need for purchasing the latest configuration (â€Å"History of American consumerism†). Besides, the further changes touched the other criterion as people started buying newer models based on considerations about appearance. Nowadays, the companies tend to seek for increasingly sophisticated tricks in order to encourage consumers to get rid  of the old product and buy the new one instead (â€Å"History of American consumerism†).According to Scott, human nature is more complex to control than a material one (Ewen, 1976). The adequate approach to distribution was and still is (to the significant extend) a guarantee for high level of efficiency and profitability. Therefore, it was a necessity to create an ideological link narrowing the prejudices and covering the traditional social gaps in needs, class, taste or region. Advertising has become an inherent part of mass distribution within industries. Marketing professionals use ad vertisements in order to encourage, or even force people to strive to purchasing certain goods, starting with small, relatively cheap items and ending with luxurious houses and cars.Advertising is a legal tool for manipulating the consciousness of consumers. The camp of advertisement supporters claim that it plays a positive role by providing people with essential information. Though, such statement is quite controversial. Advertising along with mass media industry in general have made a considerable contribution into developing certain rules or norms of consumption within the American society. Such norms depict the sufficient for high standard of living level of consumption.The influence of consumerism concept is in the progress of constant increasing and expanding. The parallels with religious beliefs might be quite reasonable within analyzing the issue. Consumerism has become an inherent part of the contemporary lifestyle. It is worth noticing that alike as the belief consumerism is ephemeral and intangible, still people can perceive its effects in everyday life. It is arguably, but it might be referred as the religion of 20th and 21st centuries (Miles, 1998). To support this statement, Miles emphasizes that it apparently enters the day-to-day life, structuring everyday experience (1998, p.1). Moreover, it is rapidly altering the forms and reasserting the influences in the new spheres (Miles, 1998).Consumerism is the concept depicting the belief that happiness and well-being  depends to a significant degree of personal consumption. Basically, it means that purchasing certain material goods is likely to increase the level of satisfaction with life. The idea includes several layers: firstly, well-being depends on the standard of living, secondly that the key satisfaction in life is centered in consumption and possession of material goods benefit. â€Å"Consuming† as an activity has become one of the most valuable and worth spending time and resources . The principles of consumerist society are developing around the idea of the increasing necessity to consume.This statement can be easily paraphrased into an elementary formula: the more you consume, the better it is for you. To add to the point, the United States is the highly developed country, meaning that the consumerist society evolved to the hyper-consumerist society. The supporting facts are sure to be found in everyday life. The Americans are mostly obsessed with the idea of buying things beyond their basic needs. Certain elements of luxury have gained the perception of necessary for happiness and sufficient standard of life. Moreover, cities are transformed into the centers of â€Å"consumerism religion†. Shopping malls provide people with the enormous quantity of mostly useless goods.The lifestyle dictated by the consumerism concept brings about a variety of adverse effects. It is reasonable to start with the consequences for an individual. Consumerism might dislod ge more valuable thing from the life of Americans. People are mostly concentrated on owning money in order to satisfy the needs imposed by advertisement, mass media industry and the consumerist society in general. The ethical and spiritual part of life, along with socializing might draw back. Moreover, the consumerist society norms might be considered as those restricting the individual freedom to a significant degree. The proclaimed standards engage in bringing to life particular patterns associated with well-being and happiness of the people within a certain framework.In addition, more global long-term consequences refer to economical, social and environmental spheres. For example, environmental sustainability is put under jeopardy as the consumerism stimulates people to buy even bigger quantity of new goods, get rid of  another enormous quantity, meaning that the nature might not be capable of overcoming the severe effects of consumerist society lifestyle. Not to mention the fa ct that manufacturing of certain products needs the nonrenewable natural resources utilizing. The economical layer is also essential as the credit cards and loans, providing the members of consumerist society with an ability to keep up with the prescribed standards, contributed to the development of the economical crisis and credit crunch.Eventually, the conducted research has shown that consumerism is not as beneficial as the mass media industry tends to depict it. Consumerism might be reduced to the concept that constant and increasing consumption of goods is a guarantee for happiness and well-being. The development of such a concept was inevitable due to the economical conditions that started with the Industrial Revolution. The manufacturers are interested in profit growth, it results in a variety and diversity of marketing tricks aimed at stimulating the buyers will and power to consume. Though, the consumerist society provoked the adverse effects of individual and global charac ter.

Saturday, September 14, 2019

Organizational Behavior Essay

There are basically 2 types of organizational structures commonly found in every organization. Namely these two are the vertical organization or the horizontal organization. (Deal, Kennedy, Deal & Kennedy, 2000). I myself have worked in both scenarios and personally favor the horizontal approach as the proposition for success is to work in teams, and cross functional teams. If a company follows a vertical approach then supervision of work becomes a much more difficult task and communication gaps arise which have been termed as the major component of project and process failures. In a horizontal organization hierarchal levels are divided in such a way that management of work becomes easier and people of different departments can share their expertise and knowledge when working together. An organization’s bottom line consists of 2 aspects, which are sales and costs. It is the major objective of any organization to maximize its sales and decrease its costs to the minimum in order to extract maximum revenues and hence increase profits and growth (Belker & Topchik,2005). Costs can be reduced when a horizontal structure is being followed as the number of channels through which information flows till it reaches its destination is reduced but opposite is in the case of a vertical approach where any information needs to cross through many channels before it reaches its destination. his results in the altering of the original message which negatively affects business plus due to the number of channels costs also increase (Porter, 1998). In the same way cross functional teams in a horizontal approach can lead to better and efficient performance as each member of the team is representing his or her department and wants to prove his or her abilities, hence this results in more efficient business processes (Singer, 2004). On the other hand a vertical approach makes it difficult for the company to work because no department is ready to share his or her data with other departments and it is difficult to manage the circulation of information throughout the organization, which results in slow business processes and inefficiency.

Friday, September 13, 2019

Merger For Success In The US Airline Industry Research Paper

Merger For Success In The US Airline Industry - Research Paper Example Prior to regulation, there were no reports of airline bankruptcy. However, since deregulation in 1978, bankruptcy has become commonplace.    Between 1978 and 2001, nine major airlines inclusive of America West, Braniff, Continental, Eastern, Pan Am and TWA and more than 100 smaller carriers declared bankruptcy or liquidated its assets (Kaps, Hamilton & Bliss, 2012). The irony is that deregulation was thought to be appropriate on the basis that previous concerns about distorted competition and monopolies had been unfounded (Kaps et. al., 2012).   As Kaps et. al. (2012) explained, government officials believed that the dynamics of the market would facilitate operations â€Å"approaching pure market competition without governmental economic regulation† (p. 7).  Prior to regulation, there were no reports of airline bankruptcy. However, since deregulation in 1978, bankruptcy has become commonplace.    Between 1978 and 2001, nine major airlines inclusive of America West, Bra niff, Continental, Eastern, Pan Am and TWA and more than 100 smaller carriers declared bankruptcy or liquidated its assets (Kaps, Hamilton & Bliss, 2012). The irony is that deregulation was thought to be appropriate on the basis that previous concerns about distorted competition and monopolies had been unfounded.   As Kaps et. al. explained, government officials believed that the dynamics of the market would facilitate operations â€Å"approaching pure market competition without governmental economic regulation†.† (p. 7). The terror attacks of September 11, 2001 introduced greater difficulties for an already struggling airline industry (Wensveen, 2011). Losses to the US airline industry following the September 11, 2001 amounted to an estimated US$17.7 billion. However, it has been argued that the failures in the airline industry cannot be entirely attributable

Thursday, September 12, 2019

Discrimination Essay Example | Topics and Well Written Essays - 250 words

Discrimination - Essay Example This harassment is termed as overt discrimination (Gregory, 2004). The Title VII of the Civil Right Act addressed the situation and declared that all decisions pertaining to employment, termination or promotion should never be based on gender, instead based on merit. The issue was addressed, and the female employee got the promotion and the male employee was subjected to punishment to discourage such behaviors (Boland, 2005). The uninformed manager could have mishandled the issue if he/she is uninformed of the Title VII of the Civil Right Act, this way there would never be any punishment administered to the gender prejudiced employee. In return, this would have led to subsequent cases of sexual harassment of the same nature in the organization (Barreto et al, 2009). The managers always determine the level of sexual harassment to be expected in an organization. Mangers that set rules that discourage sexual harassment tend to report lower cases of sexual harassment, whilst managers with rules that encourage sexual harassment experience a vast number of cases of sexual harassment (Neville,

Wednesday, September 11, 2019

Corporate Financial Management Assignment Example | Topics and Well Written Essays - 250 words

Corporate Financial Management - Assignment Example For example a few years ago Starbucks Cafe implemented a practice of donating five cents from every sale of certain beverage products towards the AIDS/HIV cause. Organizations can also improve their character by implementing a code of conduct. The use of ethical audits can help companies improve the company’s process to show greater character. The employees of corporations should also support practices that promote character. To improve their character employees can realize actions such coming to work on time everyday. Character is also developed by employees by giving the maximum effort everyday at work. Teamwork and cooperation are two attributes that show character in the workplace. Taking continued educational courses or enrolling in a graduate program is a great way for employees to promote character. The customers in the marketplace should also promote character in their interaction with businesses. Supporting companies that are socially responsible is way to show character. Customers can also promote character in the business environment by not performing actions such as stealing goods from retail stores. Another way customers can promote character is by boycotting companies that violate environmental and labor

Consequences of the Rape of Nanking Assignment Example | Topics and Well Written Essays - 500 words

Consequences of the Rape of Nanking - Assignment Example Japanese soldiers also raped 20,000 – 80,000 women. The rape of Nanking remains a contentious issue in politics. Some historical revisionists and Japanese nationalists dispute the event claiming that the massacre was exaggerated for propaganda purposes (Honda 45). There are enormous efforts by Japanese Nationalists to deny or rationalize Japanese war crimes. However, the controversy arising from the Rape of Nanking remains a stumbling block in Sino-Japanese relations. It is also a stumbling block to international relations between Japan and other Asia-Pacific nations such as South Korea and the Philippines (He 50). Many senior members of the Japanese high command were responsible for the atrocities committed by Japanese soldiers in Nanking including Emperor Hirohito. Emperor Hirohito made all the major decisions during the operation including the decision to invade China in 1937. Hirohito’s uncle, Prince Asaka was a key player in the operation because he ordered the Japanese soldiers to kill all captives. In addition, he was responsible for the gendercide against Nanking’s men. General Nakajima Kesago, commander of the 16th division was also held responsible for the Nanking Massacre. He ordered the beheading of two war prisoners as a test of his new sword (Yin and Young 284). In 1946-1947 there were war crimes trials in Nanjing. However, the trials only affected a few Japanese war criminals. Tani Hisao, a commander of the 6th division was sentenced to death in March 1947 and executed. The International Military Tribunal for the Far East (IMTFE) tried up to 30 key Japanese commanders. The tribunal tried Commander Matsui Iwane of the Central China Expeditionary Force. Matsui and other six ‘Class A’ war criminals were executed. General Yanagawa Heisuke and Lieut. General Nakajima Kesago died of a natural cause before they could be executed (Yamamoto 112). However, some members of the royal family who were also responsible for the Nanking massacre were not tried and executed.     

Tuesday, September 10, 2019

The Best Airline in the United Kingdom and Europe Research Paper

The Best Airline in the United Kingdom and Europe - Research Paper Example The airline schedules are today subjected to strict regulatory measures, which limits the flying time across Europe as a whole. To remain viable in the market, British airways must implement security and regulatory measures as stipulated by the control acts. The level of security measures that an airline puts in place also influences customer confidence and trust. Consequentially, British Airways must enforce the political security regulatory measures that are put in place by global airline control (O’Connell & Williamson, 2011). A number of economic events in the global market have also affected the performance and vibrancy of the airline industry. For example, the global economic crisis of 2008 affected a number of businesses based in the United Kingdom, which further reduced the level of airline schedules. The growth of the industry following this crisis has not significantly picked up and is currently pegged at 2% yearly. Apart from the global financial crunch, the dwindling strength of the euro has also had a significant bearing on the performance of the airline sector (Punzel, 2011). The euro has continued to weaken against the pound and this has affected the performance of British Airways. To mitigate the challenges created by the meltdown, most businesses and individuals in the United Kingdom and the United States have cut down on their spending and travels, a situation that has affected the performance of the airline. The high cost of fuels, which has led to an increase in the cost of air travel, has also forced companies to adopt other cheaper alternatives such as teleconferencing (Balmer, Stuart & Greyser, 2009).

Monday, September 9, 2019

Communication Plan Final Proposal Essay Example | Topics and Well Written Essays - 250 words

Communication Plan Final Proposal - Essay Example In either way, the customer will be disappointed if the bug is removed and if it will be ignored (Best Game Productions, 2015). From the motto of the CEO â€Å"An ethical company is a thriving business†. To maintain the ethics of the company and to retain the consumer loyalty, the video game has to be released containing the bug. Eventually, the company will implant some measures to employ a technician who will work on complete removal of the threat. The stakeholders are requested to comply with the decision made by the management. Once they release the game in the planned period, the future games will be developed in a more advanced manner that bug will have no room. According to the ground rules of the company’s ethical code, it states explicitly on how to deal with the consumer and also upholding the business’s name (Best Game Productions, 2015). To instill honesty and integrity, the consumer has to know the truth about the effect that will result if they buy a product containing a

Sunday, September 8, 2019

Industrial standard Syringe Essay Example | Topics and Well Written Essays - 750 words

Industrial standard Syringe - Essay Example The present paper deals with a syringe’s low Reynolds number flow. This scenario presents itself in the slow regulated intravenous fusion of drugs and fluids in laboratories or hospitals. For instance, in indicator-dilution experiments, the common values for the Reynolds number are Re= 0.07 (50cc syringe at 1cc/min or Re= 0.015(10cc syringe at 0.1 cc/min). A calibrated infusion pump is often used in maintaining the rates of infusion at constants. In figure 1 the plunger is moving to the left in a cylinder; fluid is pumped through a hollow needle of a diameter that is often less than 3% of the cylinder’s diameter. Because of the geometry the fluid dynamics can be divided into 2 parts: the flow in the needle and the flow in the cylinder. Dagan, Weinbaum and Pfeffer [1] solved the flow in the needle (orifice). They concluded that the velocity profile is mostly Poiseuille, with end effects maintained at a length of just  ¼ the diameter of the needle. In the sections that follow we will examine the cylinder region, with the needle hole estimated by a sink. x’s partial differentiation is numerically solved using finite difference techniques, which result in an estimation for x at every grid point. In the middle way from all borders, standard difference equations are applied in the estimation of the partial derivatives. Close to the borders, multiple standard equations are required. These new difference equations, using both partials and values of x on the borders, were derived via the symbolic manipulation package, SMP. All the finite difference estimations applied are provided in Appendix A. The finite difference estimation produces results in a linear system of equations Ax = b, with dimension being 2500 for a basic 50 x 50 grid. Due to the fact that the boundary conditions are asymmetric and difference equations using known derivatives are used, the coefficient matrix A is